PAPA - a method for predicting prion forming propensity

Enter an amino-acid sequence in the box, or select a sequence here:

Result will appear here:


If you wish to use PAPA on a genomewide scale, you can download a Python script that implements the method.


If you use PAPA please cite:
James A. Toombs, Michelina Petri, Kacy R. Paul, Grace Y. Kan, Asa Ben-Hur, and Eric D. Ross. De novo design of synthetic prion domains. PNAS, 2012.


This website was constructed by Chuck Anderson.

This material is based upon work supported by the National Science Foundation under Grant No. 1023771. Any opinions, findings and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation (NSF).